DAB2IP anticorps (AA 950-1000)
Aperçu rapide pour DAB2IP anticorps (AA 950-1000) (ABIN7451727)
Antigène
Voir toutes DAB2IP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 950-1000
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Fonction
- Rabbit anti-DAB2IP Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- between AA 950 and 1000
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Isotype
- IgG
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Indications d'application
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- DAB2IP (DAB2 Interacting Protein (DAB2IP))
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Autre désignation
- DAB2IP
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Sujet
- Background: DAB2-interacting protein (DAB2IP) functions as a Ras GTPase-activating protein. Through its interaction with MAP3K5, it disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. DAB2IP also Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. DAB2IP may act as a tumor suppressor gene [taken from the Universal Protein Resource (UniProt) Q5VWQ8].
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ID gène
- 153090
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UniProt
- Q5VWQ8
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Pathways
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation
Antigène
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